This was easily the most incredible hike I've experienced around Jackson Hole (and I live here). The amazing landscape (views of the Tetons from South, West and North) was perfectly complemented with an equally impressive display of wildflowers. From the lush canyons, alpine lakes, and crystal clear creeks to the high shelf 'moonscape' of Death Canyon Shelf, there were flowers everywhere along the way. Abundant wildlife (deer, elk, moose, bear, bald eagles, etc). Our group of 6 took four days to cover the nearly 40 miles beginning at the top of the Jackson Hole Mountain Resort Tram, exiting through Paintbrush Canyon to the String Lake Picnic Area.
The last day was the most grueling, starting at our campsite (elevation ~8,700 ft) below Lake Solitude, heading up over the Paintbrush Divide pass (elevation ~10,700 ft) and down into Paintbrush Canyon to String Lake (elevation ~6,900 ft). I wouldn't recommend that last leg in reverse to the faint of heart. For a day hike, Cascade Canyon to Lake Solitude is more advisable (still a ~2,000 ft elevation gain).
During our journey, we encountered people from all over the world who had come to hike this trail, and all seemed just as impressed as our 'local' group with the fruits of this adventure. Every step of this hike was worthy of the grandeur of the Tetons. That's no small compliment.