Sikeston Missouri Hotels, Motels & Lodging

Check out our list of Sikeston, Missouri hotels, motels and other travel lodging options below. Hotels are listed by their proximity to downtown Sikeston. Click on any hotel from the list below to view information, details, and current rates, and to make reservations online.

 
Holiday Inn Express SIKESTON

Map Marker Holiday Inn Express SIKESTON

120 S. INTERSTATE DRIVE, Sikeston, MO

Rooms begin at $110.00

3 miles from Sikeston city center.

Drury Inn And Suites Sikeston

Map Marker Drury Inn And Suites Sikeston

2608 E. MALONE, Sikeston, MO

Rooms begin at $109.99

2 miles from Sikeston city center.

Americas Best Value Inn

Map Marker Americas Best Value Inn

220 South Interstate Dr, Sikeston, MO

Rooms begin at $89.95

3 miles from Sikeston city center.

Super 8 Sikeston/Miner Area

Map Marker Super 8 Sikeston/Miner Area

2609 E Malone, Sikeston, MO

Rooms begin at $64.99

2 miles from Sikeston city center.

Country Hearth Inn Sikeston

Map Marker Country Hearth Inn Sikeston

100 Matthews Lane, Sikeston, MO

Rooms begin at $45.89

2 miles from Sikeston city center.

Comfort Inn & Suites

Map Marker Comfort Inn & Suites

109 Matthews Lane, Sikeston, MO

Rooms begin at $106.65

2 miles from Sikeston city center.

Days Inn Sikeston

Map Marker Days Inn Sikeston

1330 South Main Street, Sikeston, MO

Rooms begin at $64.95

1 mile from Sikeston city center.

Pear Tree-Thrifty Inn Sikeston

Map Marker Pear Tree-Thrifty Inn Sikeston

2602 East Malone, Sikeston, MO

Rooms begin at $84.99

1 mile from Sikeston city center.

Pear Tree Inn Sikeston

Map Marker Pear Tree Inn Sikeston

2602 Rear East Malone, Sikeston, MO

Rooms begin at $49.99

2 miles from Sikeston city center.

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Trails Near Sikeston

  • Horseshoe Lake Conservation Area Olive Branch, IL (Birding)
    This area serves as one of the most ornithologically significant links to the state’s past. Birding pioneers observed breeding species here that have disappeared from Illinois, possibly forever. Speci...

  • Columbus - Belmont State Park Trail Columbus, KY (Hiking)
    A Mississippi River bluff with a magnificent view. This little hike, the second shortest in the book, is included because it takes you along a bluff high above the Mississippi River with stupendous up...

  • Columbus - Belmont State Park Campground Columbus, KY (Campgrounds)
    You won’t believe the trees at this park. There are some huge ones—cottonwoods, sugar maples, and oaks—throughout this preserve located on dramatic bluffs of the Mississippi River. If it’s summer duri...

  • Ballard Wildlife Management Area Bandana, KY (Flatwater Paddling & Canoeing)
    Located in Ballard County in the far northwestern corner of the state along the Ohio River, the Ballard Wildlife Management Area (BWMA) is easily one of the most unusual water resources in the state o...

  • Reelfoot National Wildlife Refuge Trail Hickman, KY (Hiking)
    A quiet cove on the upper reaches of Reelfoot Lake. This hike crosses the Long Point Unit, starting in marshland on the Kentucky side and ending in Tennessee at a scenic cove full of water lilies, bal...

  • River and Hill Country: Cape Girardeau to Grand Tower, MO/IL Cape Girardeau, MO (Scenic Drives)
    A 70-mile drive starting in Cape Girardeau and following the eastern Ozark border on both sides of the Mississippi River. Located on the easternmost edge of the Ozarks, this drive follows the rugged r...

  • Obion Creek: US 51 to Whaynes Corner Columbus , KY (Flatwater Paddling & Canoeing)
    Obion Creek drains the south-central portion of the Jackson Purchase area in far western Kentucky. Originating at the bottom of Graves County, the creek flows over a mud bottom into Hickman and Carlis...