Tristan da Cunha
When it comes to remote destinations, Tristan da Cunha is impossible to beat. The most remote inhabited archipelago in the world, Tristan da Cunha is home to just under 300 souls. The climate is a damp subtropical, with plenty of varied terrain for the determined hiker. It is also the home of the Tristan Albatross, a rare species of bird, whose entire population lives primarily on the main island. Tristan da Cunha is located in the South Atlantic, almost directly between South American and Africa.
Cape Horn
The southern tip of Tierra del Fuego, Cape Horn is the southernmost point of South America. The area offers outstandingly rugged scenery. The region is home to a number of penguins and other rare species not found in other parts of the world. The area is a challenge to hikers, but it can be even more difficult for the adventurous sailor. The waters around Cape Horn have inspired legends concerning their difficulty and danger for decades.
Death Valley
You don't necessarily have to go far to find adventurous places. One excellent example of an extreme location is the American southwest's Death Valley. The hottest, driest and lowest place in North America, Death Valley can be an exceptional place to experience desert at its most extreme. The area offers hiking, climbing, off-road driving and plenty of blistering heat. For a real challenge, try out one of the many runs through Death Valley.
Ngorongoro Crater
The world's largest volcanic caldera, Ngorongoro is an intimidating region. Located in Tanzania, 110 miles west of Arusha near the Kenyan border, the Ngorongoro Conservation Area is twice the size of Rhode Island and features an incredible diversity of wildlife. The dormant caldera acts as a fielded reserve, with zebra, elephants and wildebeest. The Ngorongoro Crater has the densest population of lions in the world. If nature isn't reason enough, the Ngorongoro Crater is also central to humankind's origins, with many of the oldest humanoid skeletons emerging from the region.