Florence South Carolina Hotels, Motels & Lodging

Check out our list of Florence, South Carolina hotels, motels and other travel lodging options below. Hotels are listed by their proximity to downtown Florence. Click on any hotel from the list below to view information, details, and current rates, and to make reservations online.

 
Holiday Inn Express Hotel & Suites FLORENCE I-95 & I-20 CIVIC CTR

Map Marker Holiday Inn Express Hotel & Suites FLORENCE I-95 & I-20 CIVIC CTR

3440 WEST RADIO DRIVE, Florence, SC

Rooms begin at $119.00

4 miles from Florence city center.

Comfort Suites Florence

Map Marker Comfort Suites Florence

2120 West Lucas Street, Florence, SC

Rooms begin at $109.99

3 miles from Florence city center.

Best Western Inn

Map Marker Best Western Inn

1808 W Lucas Street, Florence, SC

Rooms begin at $84.00

2 miles from Florence city center.

Holiday Inn Hotel & Suites FLORENCE SC @ I-95 & US HWY 52

Map Marker Holiday Inn Hotel & Suites FLORENCE SC @ I-95 & US HWY 52

1819 LUCAS ST, Florence, SC

Rooms begin at $64.00

2 miles from Florence city center.

Wingate by Wyndham Florence

Map Marker Wingate by Wyndham Florence

2123 W. Lucas Street, Florence, SC

Rooms begin at $89.00

3 miles from Florence city center.

Sleep Inn Florence

Map Marker Sleep Inn Florence

1833 Florence Park Dr. I-95 & US 52, Florence, SC

Rooms begin at $69.95

3 miles from Florence city center.

Holiday Inn Express Hotel & Suites Florence I-95 @ Hwy 327

Map Marker Holiday Inn Express Hotel & Suites Florence I-95 @ Hwy 327

2101 FLORENCE HARLLEE BLVD,I-95, EXIT 170@HWY 327-WILLISTON RD, Florence, SC

Rooms begin at $119.00

6 miles from Florence city center.

SpringHill Suites Florence

Map Marker SpringHill Suites Florence

2670 Hospitality Boulevard, Florence, SC

Rooms begin at $119.00

3 miles from Florence city center.

Econo Lodge Florence

Map Marker Econo Lodge Florence

1920 West Lucas Street, Florence, SC

Rooms begin at $46.83

2 miles from Florence city center.

Americas Best Value Inn

Map Marker Americas Best Value Inn

3024 TV Road, Florence, SC

Rooms begin at $45.00

5 miles from Florence city center.

Courtyard Florence

Map Marker Courtyard Florence

2680 Hospitality Blvd., Florence, SC

Rooms begin at $129.00

3 miles from Florence city center.

Quality Inn & Suites Civic Center

Map Marker Quality Inn & Suites Civic Center

150 Dunbarton Drive, Florence, SC

Rooms begin at $89.99

3 miles from Florence city center.

Howard Johnson Express Inn and Suites Florence SC

Map Marker Howard Johnson Express Inn and Suites Florence SC

3821 Bancroft Road, Florence, SC

Rooms begin at $62.95

6 miles from Florence city center.

Baymont Inn & Suites Florence

Map Marker Baymont Inn & Suites Florence

1826 West Lucas Street, Florence, SC

Rooms begin at $64.00

2 miles from Florence city center.

Red Roof Inn Florence Civic Center

Map Marker Red Roof Inn Florence Civic Center

2690 David McLeod Blvd, Florence, SC

Rooms begin at $71.24

4 miles from Florence city center.

Microtel Inn and Suites Florence

Map Marker Microtel Inn and Suites Florence

1912 Enterprise Drive, Florence, SC

Rooms begin at $36.76

3 miles from Florence city center.

Super 8 Florence

Map Marker Super 8 Florence

1832 1/2 Lucas Street, Florence, SC

Rooms begin at $44.17

2 miles from Florence city center.

Ramada Florence SC

Map Marker Ramada Florence SC

3311 Meadors Road, Florence, SC

Rooms begin at $59.00

6 miles from Florence city center.

Ramada Florence Center

Map Marker Ramada Florence Center

1819 West Lucas Street, Florence, SC

Rooms begin at $65.00

2 miles from Florence city center.

Residence Inn Florence

Map Marker Residence Inn Florence

2660 Hospitality Boulevard, Florence, SC

Rooms begin at $116.00

3 miles from Florence city center.

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Trails Near Florence

  • Florence Rail - Trail Florence, SC (Rail-Trails)
    In 2003, the South Carolina Governor’s Council on Physical Fitness recognized the Florence Rail-Trail Committee with a community award for its work on this tree-lined trail, which spans two miles betw...

  • Cotton and Sand Hills: Woods Bay to Cheraw Lynchburg, SC (Scenic Drives)
    A 115-mile jaunt through cotton fields, peach orchards, and forested sand hills, beginning at a boggy “Carolina bay” and ending in the pretty and historic town of Cheraw, on the banks of the Great Pee...

  • Sand Hills State Forest Campground Patrick, SC (Campgrounds)
    A prehistoric sea once covered what is now South Carolina, depositing sand over a wide area. Later, these seas retreated, leaving a region of deep, infertile hills of sand. Over time many plants and a...

  • Little Pee Dee State Park Campground Dillon, SC (Campgrounds)
    Little Pee Dee State Park is one of those overlooked and forgotten destinations that time seems to have passed by. The park exudes an atmosphere as slow moving as the Little Pee Dee River for which it...

  • Sand Hills Mountain Bike Trail Florence, SC (Mountain Biking)
    On this tight, sandy singletrack, you will constantly rub elbows with pine trees. The challenges of this action-packed loop include 90-degree turns, difficult log crossings, and a new 40-foot bridge o...

  • Cheraw State Park Florence, SC (Hiking)
    A pleasant half-day walk that passes through pine forest and red-cockaded woodpecker habitat, climaxing with bald cypresses at the head of the park's lake. Longleaf pine, blackjack oak, turkey oak, an...

  • Cheraw Nature Trail Fisher Hill, SC (Hiking)
    Cheraw State Park is South Carolina’s oldest state park with a wealth of outdoor activities including hiking and biking trails, boating, fishing, equestrian trails, and even a championship eighteen-ho...